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Home Services Prognosis - Diagnosis RESPONSE TO EGFR-TARGETED THERAPIES
RESPONSE TO EGFR-TARGETED THERAPIES PDF Print E-mail
Thursday, 08 November 2012 21:55

 

 

The followings conditions must be met for tumor response to EGFR-targeted therapies

1) KRAS (EXON 2) MUTATIONS DETECTION: no mutations present

2) BRAF (V600E) MUTATION DETECTION: no mutation present

3) PI3K (EXONS 9, 20) MUTATIONS DETECTION: no mutations present

4) EGFR expression: high expression

5) ERBB3 expression: normal expression (not overexpressed)

6) PTEN expression: normal expresssion (not deleted)

 

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