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RESPONSE TO EGFR-TARGETED THERAPIES PDF Εκτύπωση E-mail
Πέμπτη, 08 Νοέμβριος 2012 21:55
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The followings conditions must be met for tumor response to EGFR-targeted therapies

1) KRAS (EXON 2) MUTATIONS DETECTION: no mutations present

2) BRAF (V600E) MUTATION DETECTION: no mutation present

3) PI3K (EXONS 9, 20) MUTATIONS DETECTION: no mutations present

4) EGFR expression: high expression

5) ERBB3 expression: normal expression (not overexpressed)

6) PTEN expression: normal expresssion (not deleted)

 

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