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Prostate Cancer PDF Εκτύπωση E-mail
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Molecular analysis of prostate biopsy for prognosis

and targeted therapy

  • Relative gene expression

EGFR

ERBB2

ERBB3

AR

PCA3

MET

VEGFR2

PDGFRα

CXCR4

CD133

CYCLIN D1

PTEN

STATHMIN

SURVIVIN

SMAD4

SSP1

DNMT1

IGFIR

 

  • Relative quantitative gene expression for prediction of response

to chemotherapy

BCRP (platinum,irinotecan,topotecan)

MRP1 (cyclophoshamide,etoposide,vincristine)

ERCC1,BRCA1 (platinum)

TYMS (5-FU,capecitabine,pemetrexed)

PGP (doxorubicin,paclitaxel,etoposide,vincristine)

RRΜ1,RRΜ2,HUR (gemcitabine)

TUBB3,SPARC,TLE3,TAU (taxanes)

MGMT (temozolomide)

HIGH EXPRESSION

NO RESPONSE

TOPO2A

(doxorubicin,epirubicin)

TOPO1

(irinotecan,etoposide)

HIGH EXPRESSION

RESPONSE

 

Εικόνα Ημέρας

transcription_factors.jpg


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