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Breast Cancer PDF Εκτύπωση E-mail
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Molecular analysis of breast biopsy for prognosis

and targeted therapy


  • Relative gene expression

HER2

ERBB3

EGFR

ESR1α

PgR

MET

IGF1R

VEGFR2

CXCR4

CYCLIN D1

PTEN

P53

BCL2

SURVIVIN

HOXB13

IL17BR

E-cadherin

FAP


  • Relative quantitative gene expression for prediction of response

to chemotherapy

BCRP (platinum,irinotecan,topotecan)
MRP1 (cyclophoshamide,etoposide,vincristine)
ERCC1,BRCA1 (platinum)
TYMS (5-FU,capecitabine,pemetrexed)
PGP (doxorubicin,paclitaxel,etoposide,vincristine)
RRΜ1, RRΜ2,HUR (gemcitabine)
TUBB3,SPARC,TLE3,TAU (taxanes)
MGMT (temozolomide)

HIGH EXPRESSION

NO RESPONSE


TOPO2A

(doxorubicin,epirubicin)

TOPO1

(irinotecan,etoposide)

HIGH EXPRESSION

RESPONSE

 

 

Εικόνα Ημέρας

rna.jpg


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